Frequently Asked Questions
What is PIUMet?
PIUMet, a web-based tool for integrative analysis of untargeted metabolomic data. PIUMet provides as easy to use tool for discovering the biological contexts of metabolite peaks with unclear identities.
What are the inputs to PIUMet?
PIUMet can analyze both single-omic or multi-omic inputs. In the single-omic analysis, the inputs consist of only one type of molecular measurement, either untargeted lipidomics or metabolomics, targeted lipidomics or metabolomics, or proteomics. A user can further investigate any combinations of these inputs for multi-omic analysis.
The inputs from these molecular measurements are any metabolite peaks, characterized metabolites, or proteins with significantly different levels between two phenotypic conditions. For targeted metabolomics and lipidomics input, PIUMet accepts the HMDB IDs, while for proteomic inputs, PIUMet accepts gene symbols.
What a node prize means?
A user must assign a prize to each input data point to show the significance of their alterations. For example, the prizes can be considered as –log (P values) of the significance of changes between two phenotypic conditions.
What are PIUMet parameters?
What are the output of PIUMet?
For a parameter set of w, beta and mu, PIUMet provides the following results:
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