Online Motif Discovery with WebMOTIFS

Thank you for your interest in WebMOTIFs, which was first published in 2007.

Since then, many other excellent programs for motif discovery have been developed.

In February 2023, we shut down WebMOTIFs. We encourage you to seek out more up-to-date tools.

WebMOTIFS References:

Romer KA, Kayombya GR, Fraenkel E. "WebMOTIFS: automated discovery, filtering and scoring of DNA sequence motifs using multiple programs and Bayesian approaches." Nucleic Acids Research. 2007 June 21. Article Full Text

WebMOTIFS is based on the TAMO software package:
Gordon DB, Nekludova L, McCallum S, Fraenkel E. "TAMO: a flexible, object-oriented framework for analyzing transcriptional regulation using DNA-sequence motifs." Bioinformatics. 2005 May 19; 21(14):3164-3165.
You can find more documentation on TAMO, and download the software package, at